Exercise, Estrogen, and Ischemic Cardioprotection by Heat Shock Protein 70
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چکیده
منابع مشابه
Exercise, estrogen, and ischemic cardioprotection by heat shock protein 70.
Acute ischemic injury and myocardial infarction arising from coronary artery disease, despite significant strides in medical and surgical management, remain a major public problem. Sex disparity has long been recognized for coronary ischemic events: premenopausal women are at reduced risk for atherosclerotic disease than men of similar age, an advantage that vanishes after menopause.1 The benef...
متن کاملBenjamin and Elisabeth Christians Exercise , Estrogen , and Ischemic Cardioprotection by Heat Shock Protein 70
Exercise, Estrogen, and Ischemic Cardioprotection by Heat Shock Protein 70 Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 2002 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/01.RES.0000018172.10175.B6 2002;90:833-835 Circ Res. http://circres.ahajournals.or...
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ACROSS SEVERAL MAMMALIAN SPECIES, moderate to high intensity aerobic-type exercise consistently protects against experimental ischemia-reperfusion (IR) insults by mitigating IR-induced ventricular arrhythmias, pump dysfunction, and tissue death [see review (8)]. Collective understanding of exercise-induced cardioprotection against IR injury was significantly advanced by the observation that a f...
متن کاملCardioprotection by CaMKII-deltaB is mediated by phosphorylation of heat shock factor 1 and subsequent expression of inducible heat shock protein 70.
RATIONALE Ca2+/calmodulin-dependent protein kinase (CaMK)II is a multifunctional kinase involved in vital cellular processes such as Ca(2+) handling and cell fate regulation. In mammalian heart, 2 primary CaMKII isoforms, deltaB and deltaC, localize in nuclear and cytosolic compartments, respectively. Although previous studies have established an essential role of CaMKII-deltaC in cardiomyocyte...
متن کاملHeat Shock Protein 70 in Alzheimer's Disease
Alzheimer's disease (AD) is the most common neurodegenerative disease that caused dementia which has no effective treatment. Growing evidence has demonstrated that AD is a "protein misfolding disorder" that exhibits common features of misfolded, aggregation-prone proteins and selective cell loss in the mature nervous system. Heat shock protein 70 (HSP70) attracts extensive attention worldwide, ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2002
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000018172.10175.b6